Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
2 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.79 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.2 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
0.699 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
27.1 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
2.71 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
4.24 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Additional information

PNECs were derived from the study with the most sensitive species available for each compartment/endpoint.

Conclusion on classification

Acute toxicity:

Based on the results obtained in aquatic toxicity studies with a structural analogue of the substance, MTHPA, 4 -MTHPA need not be classified and labelled according to Directive 67/548/EEC (DSD) and Regulation 1272/2008/EC (CLP).

Chronic toxicity:

Based on the results obtained in long-term aquatic toxicity studies with a structural analogue of the substance, MTHPA, 4 -MTHPA need not be classified and labelled according to Directive 67/548/EEC (DSD) and Regulation 1272/2008/EC (CLP).

Overview of Results used for Classification and Labelling:

Fish, short-term, freshwater: LC50 (96 h)> 100 mg/L (Anonymous, 1997)

Fish, long-term, freshwater: NOEC(14 d) = 100 mg/L (Anonymous, 1997)

Daphnia magna, short-term, freshwater: LC50 (48 h) = 130 mg/L (Anonymous, 1997)

Daphnia magna, long term, freshwater: NOEC (21d) = 20 mg/L (Vertesi, 2010)

Algae, freshwater: LC50 (72 h) = 68 mg/L (Anonymous, 1997)

Hydrolysis: abiotic degradation = 5.69 min at 12 deg Cand pH 7