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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

In a 14 d long-term toxicity test to fish no toxic symptoms were observed (LC50>100mg/L).

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
100 mg/L

Additional information

The 14-day-chronic toxicity of tetrahydromethylphthalic anhydride (MTHPA) to Oryzias latipswas studied under flow through conditions. Fish were exposed to control and test chemical at nominal/measured concentrations of 0 and 100 mg/L. The 14 day LC50/EC50 based on mortality was > 100 mg/L. The 14-day NOEC was 100 mg/L. No toxic symptoms were observed.This study is classified as acceptable and satisfies the guideline requirements for a chronic toxicity study with freshwater fish.