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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

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Administrative data

Link to relevant study record(s)

Description of key information

Tetrahydrothiophene was found to be hydrolytically stable. Less than 10% hydrolysis was observed in each buffer solution after incubation for 5 days.

Key value for chemical safety assessment

Additional information

Meinerling (2010) is a GLP-compliant study following OECD guideline 111. There were some deviations from the study plan in the storage of the sample and the use of acetonitrile as a vehicle. The use of acetonitrile as a vehicle is included in the guidelines if necessary for the test substance and so the deviations are not expected to have affected the experiment results. The study is considered reliable and suitable for use for this endpoint.