Registration Dossier
Registration Dossier
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EC number: 203-728-9 | CAS number: 110-01-0
Endpoint summary
Administrative data
Description of key information
Additional information
The key study for the biodegradation of tetrahydrothiophene (Thiebaud 1998) is a GLP, guideline proprietary study, which is considered suitable for use. These results, along with the supporting QSAR calculation, indicate that tetrahydrothiophene is not biodegradable. The key study for hydrolysis (Meinerling 2008) is a GLP-compliant, guideline study, which indicates that tetrahydrothiophene is hydrolytically stable. The key study for phototransformation (Atkinson 1989) indicates that tetrahydrothiophene would react in the atmosphere with a half-life of between 0.8 and 1.8 days. The substance is not expected to bioaccumulate or adsorb to suspended solids and sediments as the predicted log Kow is <3 (IPCS 1998).
These results indicate that tetrahydrothiophene may persist in the environment because the substance is not biodegradable, but it is predicted not to bioaccumulate or adsorb to the suspended solids or sediment in water. Although tetrahydrothiophene is highly soluble in water, the Henry's Law Constant of 36.48 Pa-m3/mol indicates that it is expected to volatilise significantly.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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