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Short-term toxicity to aquatic invertebrates

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Description of key information

In a study performed according to OECD TG 202 exposure of Daphnia magna to the test item gave a 48-h EL50 value of > 100 mg/L loading rate WAF. The NOELR was 100 mg/L loading rate WAF.

Key value for chemical safety assessment

Additional information

A study was performed to assess the acute toxicity of the test item to Daphnia magna. The method followed was designed to be compatible with OECD TG 202, referenced as Method C.2 of Commission Regulation (EC) No. 440/2008.

Due to the low aqueous solubility and complex nature of the test item, for the purposes of the test, the test medium was prepared as a Water Accommodated Fraction (WAF).

Following a preliminary range-finding test, twenty daphnids (4 replicates of 5 animals) were exposed to a Water Accommodated Fraction (WAF) of the test item at a single nominal loading rate of 100 mg/L for 48 hours at a temperature of approximately 20 deg C under static test conditions. The number of immobilized Daphnia and any adverse reactions to exposure were recorded after 24 and 48 hours.

Chemical analysis of the test preparations at 0 and 48 hours showed measured test concentrations of 77 and 81 mg/L respectively. Given that the toxicity cannot be attributed to a single component or a mixture of components, but to the test item as a whole, the results were based on nominal loading rates only.

Exposure of Daphnia magna to the test item gave a 48-h EL50 value of > 100 mg/L loading rate WAF. The NOELR was 100 mg/L loading rate WAF.