Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 203-470-7 | CAS number: 107-18-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 3.2 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 3.2 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.32 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 12.7 µg/kg sediment dw
- Extrapolation method:
- sensitivity distribution
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 1.27 µg/kg sediment dw
- Extrapolation method:
- sensitivity distribution
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 3.68 µg/kg soil dw
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 0.33 mg/kg food
- Assessment factor:
- 90
Additional information
Short-term toxicity of allyl alcohol to freshwater fish, invertebrates and algae has been determined experimentally. Fish proved to be the most sensitive indicator of toxicity and hence the 96h LC50 value for Pimephales promelas was used as the critical value for calculation of PNEC values for freshwater and marine organisms. The PNEC for STP microbes was calculated from an OECD 301C guideline ready biodegradation study which suggested no evidence of inhibition of microbial inoculum at a concentration of 100 mg/l allyl alcohol. No data were available for allyl alcohol to evaluate sediment toxicity and so the sediment PNEC (for freshwater and marine) were generated using the Equilibrium Partition Method in combination with the derived freshwater PNEC. Short-term terrestrial toxicity data was evaluated and the lowest EC50 obtained from short-term plant toxicity study (L. sativa) was used to derive the soil PNEC.
Conclusion on classification
Based on the LC50 result in the 96h acute toxicity to fish test (0.32 mg/l) and confirmation of being readily biodegradable, the classification of allyl alcohol is concluded to be:
- under Directive 67/548/EEC criteria, N; R50
- under Regulation 1272/2008 (CLP GHS) criteria, acute aquatic hazard category 1
- under UN GHS criteria, acute aquatic hazard category 1
Based on the NOEC from the 21 -day-chronic toxicity of allyl alcohol to Daphnia magna, the NOEC was identified as 0.919 mg/l based on the inhibited rate of reproduction. The classification of allyl alcohol is concluded to be:
- under Regulation 1272/2008 (CLP GHS) criteria, chronic aquatic hazard category 3
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