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Classification & Labelling & PBT assessment

GHS

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General Information

Implementation:
EU
Type of classification:
harmonised classification
Remarks:
  • Acute oral toxicity. A newly conducted GLP OECD guideline compliant study reported an LD50 =361 mg/kg for Ni sulfate hexahydrate, which confirms classification for acute oral toxicity under the 1st ATP to the CLP (EPSL, 2009).
  • Acute inhalation toxicity. As data were not available at the time of classification, the EU Risk Assessment based the classification for acute inhalation toxicity on read-across from the oral data. However, a newly conducted GLP OECD guideline compliant study reported an LC50 =2.48 mg/L for Ni sulfate hexahydrate, which confirm the classification for acute inhalation toxicity under the 1st ATP to the CLP Regulation (EPSL, 2009).

Related composition

Related composition:
Nickel sulphate (anhydrous form)
Nickel sulphate (hydrates)
Nickel sulphate (anhydrous form) - company specific

Classificationopen allclose all

Explosives
Reason for no classification:
data conclusive but not sufficient for classification
Flammable gases and chemically unstable gases
Reason for no classification:
data conclusive but not sufficient for classification
Aerosols
Reason for no classification:
data conclusive but not sufficient for classification
Reason for no classification:
hazard class not assessed
Oxidising gases
Reason for no classification:
data conclusive but not sufficient for classification
Gases under pressure
Reason for no classification:
data conclusive but not sufficient for classification
Flammable liquids
Reason for no classification:
data conclusive but not sufficient for classification
Flammable solids
Reason for no classification:
data conclusive but not sufficient for classification
Self-reactive substances and mixtures
Reason for no classification:
data conclusive but not sufficient for classification
Pyrophoric liquids
Reason for no classification:
data conclusive but not sufficient for classification
Pyrophoric solids
Reason for no classification:
data conclusive but not sufficient for classification
Self-heating substances and mixtures
Reason for no classification:
data conclusive but not sufficient for classification
Substances and mixtures which in contact with water emit flammable gases
Reason for no classification:
data conclusive but not sufficient for classification
Oxidising liquids
Reason for no classification:
data conclusive but not sufficient for classification
Oxidising solids
Reason for no classification:
data conclusive but not sufficient for classification
Organic peroxides
Reason for no classification:
data conclusive but not sufficient for classification
Corrosive to metals
Reason for no classification:
data lacking
Desensitized explosives
Reason for no classification:
data lacking
Acute toxicity - oral
Hazard category:
Acute Tox. 4
Hazard statement:
H302: Harmful if swallowed.
Acute toxicity - dermal
Reason for no classification:
data conclusive but not sufficient for classification
Acute toxicity - inhalation
Hazard category:
Acute Tox. 4
Hazard statement:
H332: Harmful if inhaled.
Skin corrosion / irritation
Hazard category:
Skin Irrit. 2
Hazard statement:
H315: Causes skin irritation.
Serious eye damage / eye irritation
Reason for no classification:
data conclusive but not sufficient for classification
Respiratory sensitisation
Hazard category:
Resp. Sens. 1
Hazard statement:
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
Skin sensitisation
Hazard category:
Skin Sens. 1
Hazard statement:
H317: May cause an allergic skin reaction.
Aspiration hazard
Reason for no classification:
data lacking
Reproductive toxicity
Hazard category:
Repr. 1B
Hazard statement:
H360D: May damage the unborn child.
Specific effect:
Perinatal mortality
Effects on or via lactation
Reason for no classification:
data conclusive but not sufficient for classification
Germ cell mutagenicity
Hazard category:
Muta. 2
Hazard statement:
H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
Carcinogenicity
Hazard category:
Carc. 1A
Hazard statement:
H350i: May cause cancer by inhalation.
Route of exposure:
inhalation
1. Specific target organ toxicity - single (STOT-SE)
Reason for no classification:
data conclusive but not sufficient for classification
1. Specific target organ toxicity - repeated (STOT-RE)
Hazard category:
STOT Rep. Exp. 1
Hazard statement:
H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
Affected organs:
other: Respiratory tract only
Route of exposure:
inhalation
1.
Concentration range (%):
>= 20
Hazard categories:
Skin Irrit. 2
2.
Concentration range (%):
>= 0.01
Hazard categories:
Skin Sens. 1
3.
Concentration range (%):
>= 1
Hazard categories:
STOT Rep. Exp. 1
4.
Concentration range (%):
>= 0.1 - < 1
Hazard categories:
STOT Rep. Exp. 2
Hazardous to the aquatic environment (acute / short-term)
Hazard category:
Aquatic Acute 1
Hazard statement:
H400: Very toxic to aquatic life.
Hazardous to the aquatic environment (long-term)
Hazard category:
Aquatic Chronic 1
Hazard statement:
H410: Very toxic to aquatic life with long lasting effects.
M-Factor acute:
1
M-Factor chronic:
1
Hazardous to the ozone layer
Reason for no classification:
data conclusive but not sufficient for classification

Labelling

Signal word:
Danger

Hazard pictogram

GHS08: health hazard
GHS07: exclamation mark
GHS09: environment

Hazard statements

H350i: May cause cancer by inhalation.
H341: Suspected of causing genetic defects <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
H360D: May damage the unborn child.
Perinatal mortality
H372: Causes damage to organs <or state all organs affected, if known> through prolonged or repeated exposure <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard>.
Affected organs: Respiratory tract only; Route of exposure: Inhalation
H332: Harmful if inhaled.
H302: Harmful if swallowed.
H315: Causes skin irritation.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
H317: May cause an allergic skin reaction.
H410: Very toxic to aquatic life with long lasting effects.

Notes