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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

22-d NOEC (reproduction)  = 3.64 mg/L

Based on the GHS, no chronic toxicity is anticipated at an NOEC or EC10 > 1 mg/L.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
3.64 mg/L

Additional information

In a 22-d chronic reproduction test on Daphnia magna, according to OECD 2011 (BASF SE, 2017), the NOEC was determined to be 3.64 mg/L (based on time-weighted mean concentrations).

In addition, the long-term effect was estimated using the estimation model ECOSAR v1.11 implemented in EPISuite v4.11; a chronic value of 4.5 mg/L was calculated. The substance was within the applicability domain, but as long-term prediction by the model has been developed based on a small data pool (training set: n < 5), the modeled results have a high uncertainty. Therefore, the results of this QSAR model are disregarded.