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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

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Description of key information

Readily biodegradable (according to OECD criteria).

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable
Type of water:

Additional information

Following a F26-25 guideline which is comparable to the Closed Bottle test (OECD 301D), DMAPA was determined to be readily biodegradable, but it failed the 10-d window according to the initial assessment (OECD SIDS, 2003). However, according to OECD TG 301D a 14-d window may be used instead of the 10-d window to determine the ready biodegradability of a test substance if the test would become unwieldy due to a large number of test bottles. In the mentioned Closed Bottle test with non-adapted activated sludge the degradation after 5 days had not yet started (0%), but after 10 and 20 days degradation reached 56% and 65%, respectively. Intermediate values for the degradation rate are not available. Therefore, the substance can be regarded as readily bioderadable according to OECD criteria.

The ready biodegradability of DMAPA is supported by an OECD 301A GLP study with the structurally similar substance DEAPA (CAS 104-78-9; BASF AG, 2005, report no. 21G0264/053110). In this ready test a lag phase of 10-14 days was observed. Nevertheless, the substance was considered to be readily biodegradable as the degradation reached 90 to 100% after 20 days and the 10-d window was kept.

Based on the available data for DMAPA itself and the structurally similar substance DEAPA, DMAPA is considered to be readily biodegradable according to OECD criteria.