Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Peer reviewed summary of study report

Data source

Reference
Reference Type:
secondary source
Title:
SIDS Initial Assessment Report for hydrogen chloride (CAS No: 7647-01-0)
Author:
OECD
Year:
2002
Bibliographic source:
SIAM 15, Boston USA 22-25th October, UNEP Publications

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Reference substance name:
Hydrogen chloride
EC Number:
231-595-7
EC Name:
Hydrogen chloride
Cas Number:
7647-01-0
IUPAC Name:
chloride
Details on test material:
Hydrogen chloride dosed as a 3.3 % aqueous solution.

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
238 - 277 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
In an oral administration test, the LD50 value for hydrogen chloride has been determined to be 238-277 mg/kg bw for female rats.
Executive summary:

In an oral administration test, the LD50 value for hydrogen chloride has been determined to be 238 -277 mg/kg bw for female rats.