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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Peer reviewed summary of study report

Data source

Reference
Reference Type:
secondary source
Title:
SIDS Initial Assessment Report for hydrogen chloride (CAS No: 7647-01-0)
Author:
OECD
Year:
2002
Bibliographic source:
SIAM 15, Boston USA 22-25th October, UNEP Publications

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Reference substance name:
Hydrogen chloride
EC Number:
231-595-7
EC Name:
Hydrogen chloride
Cas Number:
7647-01-0
IUPAC Name:
chloride
Details on test material:
Hydrogen chloride dosed as a 3.3 % aqueous solution.

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
238 - 277 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
In an oral administration test, the LD50 value for hydrogen chloride has been determined to be 238-277 mg/kg bw for female rats.
Executive summary:

In an oral administration test, the LD50 value for hydrogen chloride has been determined to be 238 -277 mg/kg bw for female rats.