Registration Dossier

Administrative data

Description of key information

The pH of hydrobromic acid (the strong mineral acid formed by hydrogen bromide [HBr] in water) is known to be acidic – the pH of a 62 % solution is 1.  Toxicological studies have shown that HBr gas and hydrobromic acid are well known to cause burns to skin and eyes.  This fact is reflected in the EU classification and labelling of HBr and hydrobromic acid as they are classified/labelled with the symbols "C" and "Xi" and the risk phrases "R35" and "R37".  
SKIN
Quevauviller, A., et al. (1974) reported that upon application to rat skin HBr causes more severe burns than hydrogen chloride (HCl) or hydrogen iodide (HI).

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

The pH of hydrobromic acid (the strong mineral acid formed by HBr in water) is known to be acidic – the pH of a 62 % solution is 1. Toxicological studies have shown that HBr gas and hydrobromic acid are well known to cause burns to skin and eyes. This fact is reflected in the EU classification and labelling of HBr and hydrobromic acid as they are classified/labelled with the symbols "C" and "Xi" and the risk phrases "R35" and "R37". 

Skin

Quevauviller, A., et al. (1974) reported that upon application to rat skin HBr causes more severe burns than HCl or HI.


Effects on skin irritation/corrosion: corrosive

Effects on eye irritation: corrosive

Effects on respiratory irritation: highly irritating

Justification for classification or non-classification