Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 269-682-7
CAS number: 68309-95-5
substance is of low acute toxicity following oral and dermal exposure.
The substance is not irritating either to the skin or to the eyes, and
does not possess any skin sensitisation potential. On these bases no
acute DNELs are required.
evaluating the genotoxic potential of the substance allow the conclusion
that the substance is not genotoxic. A
fully compliant OECD 422 study, under the worst condition of oral
gavage, set the parental systemic as well as the reproductive and
developmental toxicity NOEL at 1000 mg/kg bw/day, the limit dose,
because treatment did not affect any of the parameters, including FOBs
and motor activity assessments, as well as reproductive performence and
development of offspring up to day 4 of lactation. This endpoint is
considered appropriate to calculate long-term DNELs for workers
exposure. An additional assessment factor of 2 was applied because data
on reproductive and developmental toxicity are limited to the
above-mentioned OECD 422 study and no data on chronic toxicity are
together all the available toxicological information suggests that the
substance should be at most minimally absorbed.
The general population is not expected to be exposed to the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again