Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Dermal irritation
Two dermal irritation studies have been conducted according to OECD Guideline 404.
Eye irritation
Two eye irritation studies have been conducted according to OECD Guideline 405.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Dermal irritation

Two dermal irritation studies have been conducted according to OECD Guideline 404. Both are considered to be reliability 2 according to the Klimisch system but study 002 has been selected as key as it was conducted under worst-case conditions (occlusive dressing). Both studies showed that the substance does not warrant classification as a skin irritant according to the EU DSD and CLP schemes.

Eye irritation

Two eye irritation studies have been conducted according to OECD Guideline 405. Both studies are considered reliable, the first (001) being considered reliability 1 on the Klimisch scale. The second study (002) is considered key. Both studies showed that the substance does not warrant classification as an eye irritant according to the EU DSD and CLP schemes.

Respiratory irritation

No specific data on respiratory irritation are available; however, there have been no reports of similar events among the workers using the substance.

Justification for classification or non-classification

The available study data shows that although the substance can produce some irritant effects in both skin and eye these effects do not trigger labelling as either a skin or eye irritant according to the criteria of the EU DSD and CLP schemes. No other evidence is available to suggest that the substance is an irritant to either skin or eye and hence the substance has not been classified as such.