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Physical & Chemical properties

Partition coefficient

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Description of key information

log POW  =  0.6 for Dimethyl succinate (CAS 106-65-0)
log POW = 1.0 for Dimethyl glutarate (CAS 1119-40-0)
log POW = 1.4 for Dimethyl adipate (CAS 627-93-0)

Key value for chemical safety assessment

Additional information

There is one reliable key study for this endpoint. In this study (Habeck C., 2010), the partition coefficient (n-octanol / water) of Reaction mass of Dimethyl adipate (CAS627-93-0), Dimethyl glutarate (CAS1119-40-0) and Dimethyl succinate (CAS106-65-0) was determined using the HPLC- method as described in EEC Directive 92/69, A.8, the Council Regulation (EC) No. 440/2008, A.8 and in the OECD Guideline No. 117. The study was compliant with the GLP principles.

 

Six common standards, which have known log POWvalues were used as reference standards. For the determination of the dead time a thiourea solution was used. From the regression curve (log k' vs. log POW) the n-octanol / water partition coefficient (log POW) of Reaction mass of Dimethyl adipate (CAS627-93-0), Dimethyl glutarate (CAS1119-40-0) and Dimethyl succinate (CAS106-65-0) at 22 °C was calculated to be:

 

log POW = 0.6 for Dimethyl succinate (CAS 106-65-0)

log POW = 1.0 for Dimethyl glutarate (CAS 1119-40-0)

log POW = 1.4 for Dimethyl adipate (CAS 627-93-0)