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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25.11.2011 - 24.01.2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study was perfomed under GLP conditions according to OECD guideline
Reason / purpose for cross-reference:
reference to same study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
Deviations:
no
Principles of method if other than guideline:
The inhalable mass fraction defined as mass of particles which can be inhaled by nose or mouth was determined by absorption with 100 micrometer molecular sieve.
GLP compliance:
yes (incl. QA statement)
Type of method:
sieving
Type of distribution:
other: mass fraction of particle size <100nm
Percentile:
D50
Remarks on result:
other: median diameter not determined(migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)
No.:
#1
Size:
> 0 - < 100 µm
Distribution:
ca. 2.674 %
Conclusions:
The particle size of 2.674% (w/w) of the test item 2-ethylantraquinone was less than 100 µm.
Executive summary:

The proportion of test item having an inhalable particle size of less than 100 µm was determined according to OECD TG 110 by a sieve method to be 2.67%.

Description of key information

The percentage of particles with a diameter lower than 100 µm was determined to be 2.674% (w/w). 

Additional information

The proportion of test item having an inhalable particle size of less than 100 µm was determined according to OECD TG 110 by a sieve method to be 2.67%.