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EC number: 201-535-4 | CAS number: 84-51-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.116 µg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 2.7 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.012 µg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 47.6 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 4.8 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no exposure of soil expected
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 1.33 mg/kg food
- Assessment factor:
- 300
Additional information
The aquatic toxicity of the test item 2 -ethylanthraquinone was tested in short-term tests on the toxicity to algae, daphnids and fish. The tests were conducted under GLP and followed OECD TG 201, 202 and 203, respectively. Daphnids were most sensitive with an EC50 after 48h of 270 µg/L, followed by algae with an EbC50 of 280 µg/L. The ErC50 for algae was >280 µg/L and the LC50 after 96h in fish was >370 µg/L. All observed EC50/LC50 were slightly above the water solubility of the test item (245 µg/L).
The aquatic toxicity of the test item was tested in a long term-term test on the toxicity to daphnids. The test was conducted under GLP and followed OECD TG 211. Daphnids were more sensitive than algae with a NOEC of 5.8 µg/L compared to 150.0 µg/L for algae.
The effect of the test item on the respiration of activated sewage sludge was assessed in a valid GLP study performed according to OECD TG 209. The EC50 value observed after 3 hours exposure was greater than 100 mg/L and the NOEC was 100 mg/L.
No information on sediment toxicity and terrestrial toxicity is available.
Conclusion on classification
Short-term toxicity:
Daphnids were the most sensitive species with an EC50 after 48h of 270 µg/L. For algae, the EC50 biomass (not relevant for classification purposes) was 280 µg/L. No toxicity effects were observed in fish at concentrations tested up to 370 µg/L.
With an EC50 < 1.0 mg/L observed in the Daphnia study, this leads to following aquatic acute classification:
CLP: Aquatic Acute Toxicity Category 1; H400: Very toxic to aquatic life; M-Factor acute = 1.
Long-term toxicity:
According to the second amendment of Regulation (EC) No 1272/2008 (CLP), Figure 4.1.1, the classification for aquatic long term hazards preferably has to be based on data directly retrieved from aquatic long term studies. In this case two long-term studies are available, the algae toxicity test which is considered as a multi generation study and a 21-day daphnia reproduction study. According to the CLP regulation where adequate two long term studies are available the substance must be classified for long term toxicity using acute data according to table 4.1.0(b)(i or ii) and chronic data according to table 4.1.0.b(iii) with classification according to the most stringent outcome.
Classification derived from the result of the acute daphnia study with an EC50 = 0.270 mg/L and the fact that the substance is not rapidly degradable and further has a log Kow = 4.6, results in the following CLP classification:
CLP table 4.1.0.b(iii), acute ErC50 <=1mg/L: Aquatic Chronic Toxicity Category 1; H410: Very toxic to aquatic life with long lasting effects; M-Factor chronic = 1.
Classification derived from the result of the long term daphnia study with NOEC = 0.0058 mg/L and the fact that the substance is not rapidly degradable and further has a log Kow = 4.6, results in the following CLP classification:
CLP table 4.1.0.b(i), Chronic NOEC <= 0.1 mg/L: Aquatic Chronic Toxicity Category 1; H410: Very toxic to aquatic life with long lasting effects; M-Factor chronic = 10.
The most stringent outcome, obtained with chronic data, will be used for classification, labelling and packaging purposes.
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