Registration Dossier
Registration Dossier
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EC number: 203-489-0 | CAS number: 107-41-5
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Study period:
- 1984
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study without detailed documentation.
Data source
Reference
- Reference Type:
- publication
- Title:
- Inhibition of Metabolic Cooperation in Chinese Hamster V79 Cells by Various Organic Solvents and Simple Compounds
- Author:
- Chen TH, Kavanagh TJ, Chang CC & Trosko JE
- Year:
- 1 984
- Bibliographic source:
- Cell Biology and Toxicology, 1( 1):pp 155-171
Materials and methods
- Type of study / information:
- Assessment of cytotoxicity and metabolic cooperation
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Assessment of cytotoxicity and metabolic cooperation in Chinese hamster lung fibroblast V79 cells
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-methylpentane-2,4-diol
- EC Number:
- 203-489-0
- EC Name:
- 2-methylpentane-2,4-diol
- Cas Number:
- 107-41-5
- Molecular formula:
- C6H14O2
- IUPAC Name:
- 2-methylpentane-2,4-diol
- Details on test material:
- - Name of test material (as cited in study report): 2-Methyl-2,4-pentanediol
Constituent 1
Results and discussion
Any other information on results incl. tables
2 -Methyl-2,4 -pentandiol was positive in the metabolic cooperation assay and a direct correlation between cytotoxic potential and metabolic cooperation inhibiting potential was found.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
