Registration Dossier
Registration Dossier
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EC number: 204-853-1 | CAS number: 127-63-9
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.05 mg/L
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.005 mg/L
- Assessment factor:
- 500
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 1.8 mg/L
- Assessment factor:
- 100
Sediment (freshwater)
- Hazard assessment conclusion:
- no exposure of sediment expected
Sediment (marine water)
- Hazard assessment conclusion:
- no exposure of sediment expected
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no exposure of soil expected
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
For the freshwater the PNECfreshwateris derived from three chronic toxicity data: two estimated values (fish, daphnid) and a measured 72- ErC10 for algae. For deriving PNEC, the EC10 of algae is preferred over NOEC and growth rate is preferred over biomass (REACH guidances R10 and R7b). The PNEC is based on the data presented in table 1.
Endpoint |
Value (mg/l) |
Source |
Water solubility |
14.7 |
measured |
Algae 72h-ErC10 |
8.5 |
OECD 201 growth rate |
Fish NOEC |
3.8 |
Ecosar v1.1 |
Daphnid NOEC |
2.5 |
Ecosar v1.1 |
Table 1 Parameter values used for derivation of PNEC
When three chronic values are available, an assessment factor of 10 may be used. However the value for the most sensitive species (Daphnia) is an estimated value. Although the NOECs for the three species differ little, an assessment factor of 50 is applied to the Daphnid NOEC value of 2.5 mg/l, as a safe approach. The PNECfreshwateris 0.05 mg/l.
Conclusion on classification
No classification for the aquatic environment. The acute L(E)C50 for fish, Daphnid and algae is not reached at maximum measured water solubility. The estimated NOEC for fish and Daphnid and the measure 72h-EC10 for algae are above the chronic classification threshold of 1 mg/l.
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