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Diss Factsheets
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EC number: 204-853-1 | CAS number: 127-63-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 22 April 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
- Specific details on test material used for the study:
- lot nr 202011220005
Diphenyl sulphone content: 99.99 % - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- The source of test organisms was activated sludge freshly obtained from a municipal sewage treatment plant: 'Waterschap Aa en Maas', 's-Hertogenbosch, The Netherlands, receiving predominantly domestic sewage.
- Duration of test (contact time):
- 29 d
- Initial conc.:
- ca. 18 mg/L
- Based on:
- TOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium:
- Additional substrate:
- Solubilising agent (type and concentration if used):
- Test temperature: 22 +/- 2°C
- pH: 7.4 +/- 2°c
- pH adjusted: yes 1 M HCL
- CEC (meq/100 g):
- Aeration of dilution water:
- Suspended solids concentration: 12.8 mg/L
- Continuous darkness: yes
- Other:
TEST SYSTEM
- Culturing apparatus: 2 L amber glass bottles
- Number of culture flasks/concentration: Test suspension: containing test item and inoculum (2 bottles).Inoculum blank: containing only inoculum (2 bottles)
Procedural control: containing procedural control item, and inoculum (1 bottle).
Toxicity control: containing test item, procedural control item, and inoculum (1 bottle).
- Method used to create aerobic conditions:
- Method used to create anaerobic conditions:
- Measuring equipment: titration
- Test performed in closed vessels due to significant volatility of test substance:
- Test performed in open system:
- Details of trap for CO2 and volatile organics if used: Three CO2-absorbers (bottles filled with 100 mL 0.0125 M Ba(OH)2) were connected in series to the exit aeration line of each test bottle.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: yes
- Other: Sodium acetate reference control
- Reference substance:
- acetic acid, sodium salt
- Preliminary study:
- Before the start of the test (Day -1) mineral components, Milli- RO water (ca. 80 % of final volume) and inoculum were added to each bottle. This mixture was aerated with synthetic air overnight to purge the system of CO2.
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 5
- Sampling time:
- 28 d
- Results with reference substance:
- Functioning of the test system was checked by testing the procedural control item sodium acetate, which showed a normal biodegradation curve (79 % within 14 days, ).
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- Diphenyl sulphone was not readily biodegradable under the conditions of the modified Sturm test
- Executive summary:
The biodegradation in water of Diphenyl sulphone was investigated in a standard screening study OECD 301B.
Relative biodegradation values calculated from measurements performed during the test period revealed no biologically relevant biodegradation of Diphenyl sulphone (5 % and 0 %, based on ThCO2).
In the toxicity control, more than 25 % biodegradation occurred within 14 days (40 %, based on ThCO2). Therefore, the test item was considered not to inhibit microbial activity.
Functioning of the test system was checked by testing the procedural control item sodium acetate, which showed a normal biodegradation curve (79 % within 14 days ).
Reference
Description of key information
The aerobic biodegradation of diphenyl sulphone in water was determined in the OECD 301 b study. The substance is found not to be readily biodegradable.
5% and 0% degradation was calculated based on ThCo2 after 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
the test results confirm the estimated values, and it is concluded that DPS was not readily biodegradable
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