Registration Dossier
Registration Dossier
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EC number: 911-369-0 | CAS number: -
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.18 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.018 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 5.3 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 8.15 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.815 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 5.6 mg/kg soil dw
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential to cause toxic effects if accumulated (in higher organisms) via the food chain
Additional information
Conclusion on classification
The short-term LC50 or EC50 values were 15.8, 25 and 6.7 mg/l, for fish, daphnia and algae, respectively, so between 1 and 10 mg/l. Cyclacet does not meet the criteria for readily/rapidly biodegradable. It can be concluded that the substance does not need to be classified as Aquatic Acute toxic according to EU CLP (EC 1272/2008 and its amendments).
Chronic toxicity data are available for algae on the substance itself and for fish and invertebrates via read-across from the structurally similar substance Cyclaprop. The lowest NOEC / EC10 from these chronic tests is a 21d-NOEC of 1.8 mg/L for Daphnia. Therefore, based on the available chronic data in combination with its non-rapidly degradability, Cyclacet does not need to be classified for long-term hazards to the environment according to EU CLP (EC 1272/2008 and its amendments) as the NOEC/EC10 values are above 1 mg/L.
For GHS: The acute toxicity of 6.7 mg/l for Cyclacet results in Acute Cat. 2 (H401).
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