Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Adequacy of study:
supporting study

Data source

Reference
Title:
No information
Author:
Benigni, R(1989) Analysis of the national toxicology|program data on in vitro genetic toxicity tests using|multivariate statistical methods, Mutagenisis, 4(6):412-419

Materials and methods

Type of study / information:
Type: other: Multivariate statistics of four in vitro short-term tests for the prediction of mutagenicity or carcinogenicity

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
TS-Freetext:
Chemical Name: diallyl phthtalate (CAS No. 131-17-9)

Results and discussion

Applicant's summary and conclusion

Conclusions:
CL-Freetext:
The other in vitro short-term mutagenicity tests did not
complement the Salmonella typhimurium test for prediction
carcinogenicity, but were an important complement for
describing the potential genotoxicity of chemicals.

All the endpoints ,refereed in this article, of diallyl
phthalate are positive, this article says, according to the
results from the four test and the report for rodent
carcinogenicity classification by NCI/NTP and the report for
the levels of carcinogenic effects derived from Ashby and
Tennant (1988).