Registration Dossier
Registration Dossier
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EC number: 412-300-2 | CAS number: 139504-68-0 AMBER CORE
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 0.022 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.041 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.002 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 1 mg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.218 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.022 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 2 mg/kg soil dw
- Assessment factor:
- 50
- Extrapolation method:
- assessment factor
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 4.67 mg/kg food
- Assessment factor:
- 300
Additional information
Aquatic toxicology:
In the Aquatic toxicity part, 5 studies were available: one short-term toxicity to fish, Oncorhynchus mykiss (96h-LC50 = 4.1 mg/L), one short-term toxicity to daphnia, Daphnia magna (48h-EC50 = 5.9 mg/L), one long-term toxicity to daphnia, Daphnia magna (21d-EC50 = 2.4 mg/L based on immobilisation and 21d-EC50 > 1.4 mg/L based on reproduction), one study on algae, Selenastrum capricornutum (72h-ErC50 = 12 mg/L), and one study on fish (P. promelas) with a 33 d NOEC for length and body weight of 0.22 mg/L.
PNEC freshwater factor of 10 was chosen because three long-term NOECs are available (daphnia, fish and algae).
Terrestrial toxicity:
In the Terrestrial toxicity part, 2 studies were available: one toxicity study to earthworms Eisenia foetida (14d-LC50 = 390 mg/Kg soil and NOEC = 180 mg/Kg soil) and one seedling emergence toxicity study to 3 plants species: Glycine max, Lycopersicon esculentum and Avena sativa (the lowest 21d-EC50 = 150 mg/Kg soil and NOEC = 100 mg/Kg soil, based on growth).
PNEC soil factor of 50 was chosen because NOECs are available for two trophic levels (earthworms and plants).
Conclusion on classification
Classification according to the Directive 67/548/EEC: Amber Core is in Annex I and is classify as R51 -53 for the environment.
GHS classification: Aquatic Chronic 2 / H411.
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