Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 412-300-2 | CAS number: 139504-68-0 AMBER CORE
Endpoint summary
Administrative data
Description of key information
Additional information
Acute data, based on international guidelines, are available for three trophic levels: Algae, Invertebrates and Fish and are summarized in the table below.
Among all the species tested, a toxic effect was found at the three trophic levels, and the most sensitive species was fish, (Oncorhynchus mykiss). The 96h-LC50 was determined to be 4.1 mg/L. A test was performed on this species following OECD guidelines, and conducted under GLP.
Two chronic studies are available, one on Daphnia magna to assess the toxicity of Amber Core on invertebrates and one on Pimephalese promelas to assess the toxicity of Amber Core on fish.
Long term toxicity information was located for Daphnia magna (LC50 > 1.4 mg/L and LC50 = 2.4 mg/L at 21 days, based on reproduction and immobilization, respectively). The NOEC for invertebrates was considered to be 1.4 mg/L.
In the long-term toxicity to fish Pimephales promelas, a 33 d NOEC of 0.22 mg/L was obtained. Test was performed on this species following OECD guidelines, and conducted under GLP.
Organism |
EC50/LC50 (mg/L) |
NOEC (mg/L) |
Reference in IUCLID |
Acute |
|||
Fresh water |
|||
Algae |
|||
Selenastrum capricornutum |
Growth rate 72h: 12 |
Growth rate 72h: 1.5 |
6.1.5. 139504-68-0, Toxicity to aquatic algae and cyanobacteria, unknown author, 1995, K |
Biomass 72h: 5.6 |
- |
||
Aquatic invertebrates |
|||
Daphnia magna |
48h: 5.9 |
48h: 3.2 |
6.1.3. 139504-68-0, Short-term toxicity to aquatic invertebrates, Sunakawa, 1992, K |
Fish |
|||
Oncorhynchus mykiss |
96h: 4.1 |
96h: 1.8 |
6.1.1. 139504-68-0, Short-term toxicity to fish, Sunakawa, 1992, K |
Chronic |
|||
Aquatic invertebrates |
|||
Daphnia magna |
Reproduction 21d: >1.4 |
Reproduction 21d: 1.4 |
6.1.4. 139504-68-0, Long-term toxicity to aquatic invertebrates, Sunakawa, 1995, K |
Immobilisation 21d: 2.4 |
Immobilisation 21d: 1.4 |
||
Fish |
|||
Pimephales promelas |
- |
Length and weight 33d : 0.22 |
6.1.2. 139504-68-0, Long-term toxicity to fish, Goodband and Mullee, 2009, K |
A study on the toxicity of Amber Core on microorganisms is also available. Amber Core had no significant inhibitory effect on the respiration rate of activated sludge at any of the concentrations employed in the test. The EC50 of the test material could not therefore be calculated but these must be greater than 100 mg/L, the highest tested level.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
