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EC number: 412-300-2 | CAS number: 139504-68-0 AMBER CORE
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
A key study evaluating the toxicity of Amber Core (P-#620) to the earthworm (Eisenia foetida) is available. The key values for chemical safety assessment are 14d-LC50 based on mortalities at 390 mg/Kg and NOEC at 180 mg/Kg.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 390 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil macroorganisms:
- 180 mg/kg soil dw
Additional information
One key study according to the OECD guideline 207 with GLP statement is available to assess the acute toxicity of the test material (Amber Core P#620) to the earthworm (Eisenia foetida) in an artificial soil.
Following a preliminary range-finding test, earthworms were exposed in groups of 40 (4 replicates of 10 worms per concentration) to a range of concentrations of 100, 180, 320, 560 and 1000 mg/Kg of soil for a period of 14 days. The number of mortalities were determined after 7 and 14 days exposure. A positive control using chloroacetamide, conducted approximately every 6 months, was reported for reference purposes.
The 14 -Day LC50 for the test material to earthworms based on nominal test concentrations was 390 mg/Kg with 95% confidence limits of 370 -420 mg/Kg. The NOEC was 180 mg/Kg.
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