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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The result was obtained from a collection of reliable data which has been subject to peer-review and in which the original data sources are traceable.

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2002

Materials and methods

Principles of method if other than guideline:
According to Deneer et al. (1988, quoted in above report), a slow stirring method was employed to minimise the formation of emulsions and the test was conducted in triplicate at room temperature. Analysis was by gas-liquid chromatography (GLC).
GLP compliance:
no
Type of method:
other:
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
propylene oxide
IUPAC Name:
propylene oxide
Constituent 2
Reference substance name:
Methyloxirane
EC Number:
200-879-2
EC Name:
Methyloxirane
Cas Number:
75-56-9
IUPAC Name:
2-methyloxirane
Details on test material:
Test material was racemate from both R(+) and S(-) propylene oxide. This endpoint is not measured / determined with enantio-selective sensors.
Therefore the S(-) value is identical to the racemate endpoint.

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
>= 0.03 - <= 0.085
Remarks on result:
other: Test at room temperature
Details on results:
The experimental values obtained are in reasonably close agreement, (within the error margins of the experimental method).

Any other information on results incl. tables

A number of calculated log Kow values are quoted in IUCLID, ranging from -0.27 (Lipnick et al., 1987) to 0.35 (references from citation above).

Applicant's summary and conclusion

Conclusions:
A partition coefficient of 0.03 - 0.085 was obtained at room temperature for the propylene oxide in two reliable studies. A log KOW of 0.055 shall be
used for the exposure assessment.