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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

An OECD 203 study is available with Bis (2-chloroethoxy)methane (the most toxic of the three main components) . This study resulted in LC50 = 50.2 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
50.2 mg/L

Additional information

One OECD 203 study is available with one the main constituents (Bis (2-chloroethoxy)methane) which is the most toxic. ECOSAR predicted values are available for the three main constituents (including Bis (2-chloroethoxy)methane)and they are as follows:

Bis (2-chloroethoxy)methane 96 hr LC50: 125.22 mg/L (compare to measured value of 50.2 mg/L)

Ethane, 1-(2-chloroethoxy)-2-[(2-chloroethoxy)methoxy: 225.23 mg/L

1,15-dichloro-3,5,8,11,13-penta-oxa pentadecane: 96 hr LC50 = 610.849 mg/L

The predicted data show that Bis (2-chloroethoxy)methane is the most toxic of the three main components.

As a result the measured value of 50.2 mg/L is taken as the worst case and used for risk assessment purposes, without a need to perform full tests with the remaining 2 components or the complete substance mixture.