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EC number: 603-094-7
CAS number: 125904-11-2
Table 5 (Reproduced from study report)
Cumulative Mortality and Observations
1 Cumulative number of dead fish.
2 Observed Effects: AN = appear normal; C = lethargy; R = lying on
bottom of chamber; A = surfacing; E = erratic swimming.
3 This fish apparently was injured, causing a curved spine and erratic
Fathead minnows (Pimephales promelas) were exposed for 96 hours under
flow-through conditions to five nominal concentrations of dibromostyrene
(DBS) ranging from 0.63 to 10 mg/L. Based on the nominal test
concentrations, the 96-hour LC50 value was 6.2 mg/L, with a 95%
confidence interval of 5.0 to 10 mg/L. The no mortality concentration
was 2.5 mg/L and the NOEC was 0.63 mg/L. Study reportedly followed OECD
203 guidelines, but as noted above, results were reported in terms of
nominal concentrations even though the measured concentrations different
from nominal by more than 20%. In such a case, validity criteria require
that results be reported in terms of measured concentrations. Therefore
the LC50 values may be somewhat overestimated.
Palmer SJ et al (2005) was considered reliable and adequate for
assessment and use as the key study for this data requirement. The study
was conducted in accordance with the guideline OECD 203 and in
compliance with GLP. The study was assigned a reliability score of 1.
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