Registration Dossier
Registration Dossier
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EC number: 215-947-7 | CAS number: 1458-18-0
Auto flammability
Administrative data
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 15 February 2013 - 03 May 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.16 (Relative Self-Ignition Temperature for Solids)
- Version / remarks:
- (2008)
- Deviations:
- yes
- Remarks:
- The temperature of the oven was increased to 400°C although the melting temperature of the substance is lower. This has no effect on the outcome of the study.
- GLP compliance:
- yes
Test material
- Reference substance name:
- Methyl 3-amino-5,6-dichloropyrazine-2-carboxylate
- EC Number:
- 215-947-7
- EC Name:
- Methyl 3-amino-5,6-dichloropyrazine-2-carboxylate
- Cas Number:
- 1458-18-0
- Molecular formula:
- C6H5Cl2N3O2
- IUPAC Name:
- methyl 3-amino-5,6-dichloropyrazine-2-carboxylate
- Test material form:
- solid: particulate/powder
- Details on test material:
- Identification: Amiloride Compound 7
Molecular formula: C6H5Cl2N3O2
Molecular weight: 222.03
CAS Number:1458-18-0
Description: Tan powder
Batch: 206-2
Purity/Composition: 99.7 area%
Test substance storage: In refrigerator (2-8°C) protected from light, desiccated
Stability under storage conditions: Stable
Expiry date: 11 May 2014 (Retest date)
Constituent 1
Results and discussion
Relative self-ignition temperature (solids)
- Remarks on result:
- no self-ignition observed up to the melting point
Any other information on results incl. tables
No endothermic or exothermic reaction between 20°C and 400°C. After the experiment, no test substance was left in the test cube or container that was placed below the cube. It indicated that the test substance was molten and evaporated during the experiment. This is in line with the melting temperature of the substance (230°C:see endpoint 4.2).
Applicant's summary and conclusion
- Conclusions:
- The relative self-ignition test was performed (GLP-compliant study in accordance with EC A.16), not resulting in a temperature at which self-ignition of Amiloride Compound 7 took place.
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