Registration Dossier
Registration Dossier
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EC number: 246-613-9 | CAS number: 25103-09-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.91 mg/L
- EC10 or NOEC for freshwater algae:
- 0.5 mg/L
Additional information
No relevant data has been identified for isooctyl mercaptoacetate (IOTG). Existing data for 2-ethylhexyl mercaptoacetate (EHTG)
was used for covering this endpoint.
EHTG and IOTG are both C-8 esters of thioglycolic acid. In addition, both EHTG and IOTG are hydrolytically unstable and rapidly oxidize, and have as a common degradate when hydrolyzed, thioglycolic acid (TGA; CAS No. 68-11-1). In addition to TGA, the hydrolysis breakdown product for EHTG is 2-ethylhexanol (CAS No. 104-76-7), an 8-carbon alcohol. For IOTG, the hydrolysis breakdown products are TGA and iso-octanol. The iso-octanol in this case is a mixture of 8-carbon alcohols, the major isomers being methylheptanols, and dimethylhexanols. Based on the close structural similarity of EHTG and IOTG, their chemical and physical properties and behavior are expected to be similar. Melting point, boiling point, vapor pressure and water solubility values are consistent with this expectation.
The EC50 and NOEC were calculated using nominal concentrations. The results are :
The EC50 -72h was calculated to be 0,91 mg/1 and the NOEC was calculated to be 0.5 mg/L.
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