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EC number: 201-877-4
CAS number: 89-04-3
Pressure: 5.96E-05 Pa
solubility: 3.2e-05 mg/L
Kow (skin, pH= 5.5): 9.3
dose*: 4720 mg
skin area**: 1000 cm2
of stagnant air***: 1 cm
deposition: 0 hr
time observation: 4 hr
2 mL of a liquid having a viscosity similar to water will practically
wet the palms of two hands. (ca.
420 cm2). So 4.8 mL will wet all the skin surface of both hands.
It is reasonably expected more liquid will be excess and wash/fall off.
skin surface of two hands of an adult.
time observation: 4
time stratum corneum: 47.6
derm. abs.: 1e-7
derm. abs. for 2000 cm2in 1 hour (from liquid):
uptake ratio (from airborne vapour):
dermal absorption by dermal exposure to airborne vapour
inhalation absorption from airborne vapour
that Fully Respiratory Protection provides 100% efficiency:
100*X/(RX+X)= 100/(R+1)= 100/1.134= 88.2% protection against
overexposure to the substance in the form of vapour due to dermal vapour
absorption over whole body surface.
evaluation of dermal absorption indicates that after 4 hours there is no amount
of deposited substance that is absorbed within viable epidermis and
therefore that could enter in systemic circulation.
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