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EC number: 201-877-4
CAS number: 89-04-3
Table #: Irritant/corrosive response
data for each animal at each observation time of each animal from the
Score at time point / Reversibility
Max. score: 4
Max. score: 2
Max. score: 3
Average 24h, 48h, 72h
Maximum average score (including area affected, max 110)
Average time (unit) for reversion
*) Reversibility: c. = completely
reversible; n.c. = not completely reversible; n. = not reversible
Eye irritation of a structural analogue of the substance
(1,2,4 -Benzenetricarboxylic acid, mixed decyl and octyl triesters) has
been investigated in the rabbit using methods in accordance with OECD
Administration of 1,2,4 -Benzenetricarboxylic acid, mixed
decyl and octyl triesters caused no irritation reactions of the cornea
or iris. Mild conjunctival redness was seen in all animals after 1 hour
and mild discharge was noted in one animal. After 24 hours all animals
were free of symptoms. The following mean values, based on the results
from the 24 -, 48 - and 72 hour-readings were calculated: Cornea
opacity: 0.0; Iris lesion: 0.0; Redness of conjunctiva: 0.0; Oedema of
Based on the result of this study
1,2,4-Benzenetricarboxylic acid, mixed decyl and octyl triesters was
judged to be non irritating to eyes and mucosa.
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