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Toxicological information

Exposure related observations in humans: other data

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Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
other: exposure measurements
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Levels and sources of volatile organic compounds in homes of children with asthma
Author:
Chin, JY; Godwin, C; Parker, E; Robins, T; Lewis, T; Harbin, P; Batterman, S
Year:
2014
Bibliographic source:
Indoor Air, 24(4), 403-415

Materials and methods

Type of study / information:
VOC measurement
Principles of method if other than guideline:
VOC levels in 126 homes of children with asthma were measured in Detroit, Michigan, USA in total 325 visits
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl methacrylate
EC Number:
202-597-5
EC Name:
Ethyl methacrylate
Cas Number:
97-63-2
Molecular formula:
C6H10O2
IUPAC Name:
ethyl methacrylate
Details on test material:
Purity not specified, but > 98% commercial grade assumed.

Method

Ethical approval:
not specified
Details on study design:
VOC levels in 126 homes of children with asthma were measured in Detroit, Michigan, USA in total 325 visits
Exposure assessment:
measured

Results and discussion

Results:
EMA was detected (detection limit: 0.65 mg/m3) in 4% of the 325 visits with a median concentration of 0.33 mg/m3 (95% quantil: 0.58 mg/m3; max 73.74 mg/m3).

Applicant's summary and conclusion