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Short-term toxicity to aquatic invertebrates

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Description of key information

Acute daphnia: 48 hr EC50 >66 mg/L Daphnia magna 

Key value for chemical safety assessment

Additional information

For ethyl methacrylate the study in Daphnia magna showed a 48-hr EC50 of >66 mg/L. Data are available for the lower alkyl methacrylates category which indicate a trend of increasing toxicity (48 h EC50) from the acid and the methyl ester to the ester with the longest side chain in the category, 2‑EHMA. See the following table:

Summary of short-term effects on invertebrates

Ester

Invertebrate Species

EC50(mg/l)

Exposure time

Study Type

Remarks

Reference

MAA

Daphnia magna

>130b

48 h

TSCA 797.1300***(static, closed vessels)

Rel. 1

Burgess, 1990a

MMA

Daphnia magna

69b

48 h

TSCA 797.1300***(static, closed vessels)

Rel. 1

Bowman, 1990b

EMA

Daphnia magna

 >66a, c *

48 h

OECD 202 (flow-through)

Rel. 1

Putt, 1995a

n-BMA

Daphnia magna

 32a

48 h

TSCA 797.1300***(static, closed vessels)

Rel. 1

Kent et al., 1993

Daphnia magna

25.4b, c

48 h

OECD 202 (static, closed vessels)

Rel. 1

MoE, 1998a

i-BMA

Daphnia magna

 >29a, c **

48 h

OECD 202 (flow-through)

Rel. 1

Putt, 1995b

2-EHMA

Daphnia magna

> w.sol.

(4.6a, c, d)

48 h

OECD 202 (static, closed vessels)

Rel. 2

MoE,1998b[m1] 

*Only 25 % of the test organisms were immobilised at the highest achievable concentration

**only 20 % of the test organisms were immobilised at the highest achievable concentration

***comparable to OECD 202

abased on measured concentrations;bbased on analytically confirmed nominal concentrations;cdispersant used;dmost test concentrations, including the EC50were above the limit of solubility.

 [m1]New explanation re other data and use of mean