Registration Dossier

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Long-term daphnia: 21-day NOEC 18 mg/L (Daphnia magna)

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater invertebrates:
18 mg/L

Additional information

In a valid OECD 211, the 21-day LOEC for Daphnia magna was 31 mg/L; the NOEC for reproduction was 18 mg/L.

For ethyl methacrylate the long-term study in Daphnia magna showed a LOEC of 31 mg/L and a NOEC for reproduction of 18 mg/L. Data are available for the lower alkyl methacrylates category which indicate a trend of increasing toxicity (21 -d NOEC/LOEC) from the acid and the methyl ester to the ester with the longest side chain in the category, 2‑EHMA. See the following table:

Summary of long-term effects on invertebrates

Ester

Invertebrate Species

NOEC / LOEC

(mg/l)

Exposure time

Study Type

Remarks

Reference

MAA

D. magna

53a/ 110a

21 days

OECD 202 p. 2 (flow-through)

Rel. 1

Putt, 1995a

MMA

D. magna

37a/68a

21 days

OECD 202 p. 2 (flow-through)

Rel. 1

Putt, 1995b

EMA

D. magna

18a/31a

21 days

OECD 202 p. 2 (flow-through)

Rel. 1

Putt, 1995c

n-BMA

D. magna

2.6a/4.9a

21 days

OECD 202 p. 2 (flow-through)

Rel. 1

Putt, 1995d

D. magna

1.1a/ 3.4a

21 days

OECD 202 p. 2

(semi-static, closed vessels)c

Rel. 1

MoE, 1998a

2-EHMA

D. magna

0.29a, c/ 0.64a, c

21 days

OECD 202 p. 2 (semi-static, closed vessels)

Rel. 2

MoE, 1998b

D. magna

0.105a/ 0.219a

21 days

OECD 211 (semi-static, closed vessels)

Rel. 1

Schäfers, 2004b

abased on measured concentrations;bbased on analytically confirmed nominal concentrations;cdispersant used, but NOEC and LOEC within the range of solubility