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EC number: 203-815-1
CAS number: 110-91-8
animal1/animal2 (50 µL):
Mean values over 24 h, 48 h and 72 h:
Animal1: Opacity: 1.3; Chemosis: 0;
Erythema: 1.3; Iritis: 0
Animal2: Opacity: 1; Chemosis: 0; Erythema:
2; Iritis: 0
The application of 50 µL test substance
caused initially chemosis and moderate opacity and erythema. The corneal
opacity and erythema effects were not reversible within the 8 day
observation period. One animal developed ingrowing vessels at the end of
the observation period.
animal1/animal2 (100 µL):
Animal1: Opacity: 2; Chemosis: 2; Erythema:
2; Iritis: 1.3
Animal2: Opacity: 2; Chemosis: 2; Erythema:
2; Iritis: 1.3
The applicaton of 100 µL test substance
caused moderate to severe corneal opacity, erythema and chemosis. After
48 hours iritis and after 6 days staphyloma was noted. The effects were
not reversible within the 8 day observation period Severe corneal
opacity and iritis are considered to be irreversible effects to
The original BASF grading was
converted into the numerical grading according to the OECD Draize system.
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