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EC number: 203-815-1
CAS number: 110-91-8
From the water surface, the substance will not evaporate into the atmosphere.
In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.
According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.
For the assessment of morpholine (Q)SAR results were used for the estimation of the Henry’s Law constant. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.
Therefore, further experimental studies on the Henry’s Law Constant are not provided.
No experimental data are available for morpholine (CAS 110-91-8). However, the Henry's Law constant was estimated using HENRYWIN v3.20 (EPISuite v 4.11) to be 0.0115 Pa*m³/mol; this estimation refers to the uncharged molecule. The substance was within the applicability domain of the estimation model.
Based on the calculated data, it can be concluded that the substance will not evaporate into the atmosphere from the water surface.
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