Registration Dossier
Registration Dossier
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EC number: 202-879-8 | CAS number: 100-69-6
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Older data from a guinea pig sensitisation test showed that 8 of 10 animals demonstrated some degree of sensitisation, with 5 of 10 showing moderate to strong responses. 2 -Vinylpyridine was included in a validation study of the murine LLNA, and was evaluated as positive (Stimulation Index > 3). These data suggest that 2VP is sensitising.
Migrated from Short description of key information:
As 2VP is a dermal sensitiser, the risk assessment will proceed in a qualitative manner. There is no data on respiratory sensitisation, Risk management measures as recommended will protect workers from sensitising effects of this substance.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No data on respiratory sensitisation.
Justification for classification or non-classification
In order to protect workers, 2VP is classified as sensitising, and gloves are recommended to minimize skin contact. This risk management measure also suffices to protect against skin corrosion properties. 2VP is required to be classified as corrosive to the respiratory tract. The risk management measures associated with this risk will accommodate any risk for respiratory sensitisation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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