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EC number: 406-260-5
CAS number: 58834-75-6
BTN; VPO CATALYST
- oral: LD50 (rat) = 2171 mg/kg bw- dermal: LD50 (rat) > 2000 mg/kg bw
The acute oral toxicity was evaluated in study performed under GLP
according to OECD guideline 401. Five male and female Crj: CD(SD) rats
were treated with a suspension containing a concentration of up to 5000
mg/kg bw. The observed clinical signs included signs of comprised
lethargy, decreased motor activity, prone posture, ataxia and muscle
tremor, as well as bradypnoea, hyperpnoea and piloerection. Based on the
observed moratlity, the oral LD50 was found to be 2171 mg/kg bw for male
and female rats.
The acute dermal toxicity study was performed under GLP according
to OECD guideline 402. Five male and female Crj: CD(SD) rats were
exposed to the test substance in a concentration of 2000 mg/kg (limit
test) under occlusive conditions for 24 hours. Since no mortality was
observed, the LD50 was found to be >2000 mg/kg bw.
The available data on vanadyl pyrophosphate are
conclusive but not sufficient for classification according to EU and GHS criteria.
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