Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 289-214-5
CAS number: 86261-90-7
The 96 hour LC50, value for ureido methacrylate with rainbow trout was >962 mg/L.
A study was performed to assess the acute
toxicity of ureido methacrylate to rainbow trout (Oncorhynchus mykiss)
under semi-static, daily renewal conditions. This study was conducted in
accordance with the test guidelines EC Methods for Determination of
Ecotoxicity Annex to Directive 92/69/EEC Part C, Method 1 "Acute
toxicity for Fish" and OECD Guideline for Testing of Chemicals No. 203
"Fish, Acute Toxicity Test". Groups of seven juvenile fish were exposed
to concentrations, nominally 46, 100, 220, 460 and 1000 mg/L of ureido
methacrylate dissolved in water. Actual mean measured test
concentrations were 42, 93, 201, 420, 962 mg/L. Measured concentrations
ranged from 91 - 112% of nominal at 0 hours, 90 - 93% of nominal at 24
hours, 90 - 94% of nominal at 72 hours and 89 - 93% of nominal at 96
hours. Observations were made on the numbers of dead fish and the
incidence of sublethal effects after 15 minutes and 2, 4, 24, 48, 72 and
96 hours exposure.
Sublethal reactions to exposure (other than
death) were hyperventilation, coughing, erratic swimming, increased
pigmentation, and resting on base of tank. These responses were observed
only among fish exposed in the highest (962 mgll) treatment level. The
96 hour LC5, value for ureido methacrylate with rainbow trout was >962
mg/L. The 'no-observed effect concentration' for ureido methacrylate
with rainbow trout was 420 mg/L.
The acute lethal toxicity of ureido
methacrylate (50 %) to Poecilia reticulata (Guppy) was investigated
under semi-static exposure conditions over a period of 96 h. The only
applied nominal test concentration was 100 mg/L active ingredient. Since
the concentration of the active ingredient in the test material was 50
%, 200 mg/L test material were applied. The test medium was replaced
every 24 h.
HPLC analyses of the test substance
concentration were conducted at the beginning and at the end of every 24
h cycle. The analyses revealed that the test substance concentration was
satisfactorily maintained (>80 %) over the whole incubation time of 96
At the nominal concentration of 100 mg/L
active ingredient none of a total of seven fish died after 96 h of
exposure. No mortality was also observed in the blank control.
Other toxic effects than mortality, e.g.
loss of coordination, hypo- or hyperactivity and swimming on the back,
were not observed. The no-observed-effect concentration (NOEC) was >100
mg/L active ingredient. 100 % mortality (LC100) could not be detected.
Based on the binominal theory, the absence of mortality provides at
least 99 % confidence that the LC50 is greater than the applied nominal
test concentration of 100 mg/L active ingredient (>200 mg/L test
The acute lethal toxicity (OECD 203) of Hydroxyethylimidazolidone
Methycrylate to Danio rerio was under static exposure over 96 hours. The
LC50 was greater tahn 100 mg/l. (Arkema, 2003)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again