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EC number: 937-260-8
CAS number: -
Based on the available data, no structural alerts and no indications for a carcinogenic potential are identified.
Based on the overall weight of evidence, the
available data on the carcinogenic potential of the analogue substance
are conclusive but not sufficient for classification according to DSD
(67/548/EEC) and CLP (1272/2008/EC) criteria.
Therefore, using the principle of
read-across, Vinasses, residue of fermentation, depotassified is not
classified according to DSD (67/548/EEC) and CLP (1272/2008/EC) criteria.
This information is not
available for the analogue substance (Vinasses).
According to the REACh
regulation (1907/2006/EC), a carcinogenicity study may be proposed by
the registrant or may be required by the Agency in accordance with
Articles 40 or 41 if the substance has a widespread dispersive use or
there is evidence of frequent or long-term human exposure, and the
substance is classified as mutagen category 3 or there is evidence from
repeated dose studies that the substance is able to induce hyperplasia
and/or pre-neoplastic lesions.
There is no evidence, that
the analogue substance causes carcinogenicity by a direct genotoxic
mechanism as the results of the available in vitro and in vivo
genotoxicity studies (mutagenicity and cytogenicity) were negative.
Moreover, in the available subacute and subchronic repeated dose
toxicity studies no evidence for hyperplasia or preneoplastic lesions
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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