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EC number: 937-260-8
CAS number: -
and figures of the Preliminary Irritation study and Main study have been
included in the attached document "LLNA tables and figures".
Preliminary irritation study:
No irritation and no signs of systemic
toxicity were observed in any of the animals examined.
Brown remnants of the test substance were
present at 100% but did not hamper scoring of the ears. Based on these
results, the highest test substance concentration selected for the main
study was a 100% concentration.
results - main study:
No irritation of
the ears was observed in any of the animals examined. Brown
remnants of the test substance were present at 100% but did not hamper
scoring of the ears.
auricular lymph nodes at 100% were enlarged in size. The auricular lymph
nodes at 25 and 50% were considered normal in size. No macroscopic
abnormalities of the surrounding area were noted in any of the animals.
weights and body weight gain of experimental animals remained in the
same range as controls over the study period. The slight body weight
loss, noted in some animals, was considered not toxicologically
mortality occurred and no symptoms of systemic toxicity were observed in
the animals of the main study.
EC3 value (the estimated test substance concentration that will give a
SI =3) of 57.4% was calculated.
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