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EC number: 825-814-0
CAS number: 222721-94-0
Compared to controls, substantial changes in
certain dynamic factors evaluated (body weight, cerebral perfusion
pressure, and hematological parameters early in the study in 250 mg/kg
dose groups. However, toward the end of the study, practically none of
the differences between test and control animals were considered
substantial. Dosing with 50 mg/kg did not result in remarkable changes
in any of the dynamic factors studied.
It was concluded that the test substance did
not induce embryotoxicity, and did not affect the growth and development
of the progeny. No difference in number of animals born per pregant
female were noted.
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