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Physical & Chemical properties

Particle size distribution (Granulometry)

Administrative data

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018-03-07
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187
Principles of method if other than guideline:
recognized international standard
GLP compliance:
yes
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
EC Number:
928-779-0
Molecular formula:
C18-H21-N-O4 x HBr
IUPAC Name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
Test material form:
solid: particulate/powder

Results and discussion

Particle sizeopen allclose all
Key result
Percentile:
D50
Mean:
6.62 µm
Remarks on result:
other: Mean of three measurements 6.705 µm, 6.610 µm and 6.537 µm
Percentile:
D10
Mean:
1.62 µm
Remarks on result:
other: Mean of three measurements 1.637 µm, 1.614 µm and 1.596 µm
Percentile:
D90
Mean:
26.55 µm
Remarks on result:
other: Mean of three measurements 26.732 µm, 26.570 µm and 26.388 µm

Applicant's summary and conclusion

Conclusions:
The L10 D (v, 0.1) was determined to be 1.62 µm, the L50 D (v, 0.5) was determined to be 6.62 µm and the L90 D (v, 0.9) was determined to be 26.55 µm.