Registration Dossier
Registration Dossier
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EC number: 928-779-0 | CAS number: -
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Mar 1 - 7, 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: CIPAC MT 187
- Principles of method if other than guideline:
- recognized international standard
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of particle tested:
- primary particle
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 1-(3,5-dihydroxyphenyl)-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethan-1-one hydrobromide
- EC Number:
- 928-779-0
- Cas Number:
- 1178555-23-1
- Molecular formula:
- C18-H21-N-O4 x HBr
- IUPAC Name:
- 1-(3,5-dihydroxyphenyl)-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethan-1-one hydrobromide
- Test material form:
- solid: particulate/powder
Constituent 1
Results and discussion
Particle sizeopen allclose all
- Key result
- Percentile:
- D50
- Mean:
- 6.62 µm
- Remarks on result:
- other: Mean of three measurements 6.705 µm, 6.610 µm and 6.537 µm
- Percentile:
- D10
- Mean:
- 1.62 µm
- Remarks on result:
- other: Mean of three measurements 1.637 µm, 1.614 µm and 1.596 µm
- Percentile:
- D90
- Mean:
- 26.55 µm
- Remarks on result:
- other: Mean of three measurements 26.732 µm, 26.570 µm and 26.388 µm
Applicant's summary and conclusion
- Conclusions:
- The L10 D (v, 0.1) was determined to be 1.62 µm, the L50 D (v, 0.5) was determined to be 6.62 µm and the L90 D (v, 0.9) was determined to be 26.55 µm.
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