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Administrative data

Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
GLP compliance:
yes (incl. QA statement)
Type of method:
pycnometer method

Test material

Constituent 1
Chemical structure
Reference substance name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
EC Number:
928-779-0
Molecular formula:
C18-H21-N-O4 x HBr
IUPAC Name:
1-(3,5-Dihydroxyphenyl)-1-oxo-2-(N-1-(4-methoxyphenyl)isopropylamino)ethane Hydrobromide
Test material form:
solid: particulate/powder

Results and discussion

Density
Key result
Type:
relative density
Density:
1.441 other: dimensionless
Temp.:
19.99 °C

Any other information on results incl. tables

The density of the test item determined two times with individually prepared samples.

The quality criteria of the measurement (chapter3.8) were fulfilled. The data, the mean of the densities, and its relative deviation are presented in Table2 and Table3.

 

Table2:          Weight of test item

Weight No.

Vessel
empty
[g]

Vessel +
test item
[g]

Weight
test item
[g]

1

6.5645

10.6263

4.0618

2

6.5643

11.2406

4.6763

 

 

Table3:          Density ofTH 1165 Keton I Br

Weight

Determined

Weight

Temperature

Density

Relative

No.

sample volume

test item

 

 

Density

 

[cm3]

[g]

[°C]

[g/cm3]

[-]

1

2.81618

4.0618

19.99

1.4423

1.4423

2

3.24920

4.6763

19.99

1.4392

1.4392

 

 

mean:

19.99

1.4408

1.4408

 

 

absolute deviation:

0.0

0.0031

0.0031

 

 

relative deviation [%]:

0.0

0.22

0.22

 The relative density of TH 1165 Keton I Br was determined to be 1.4408 relating to the density of water at 4 °C (0.999972 g/cm3).

Applicant's summary and conclusion

Conclusions:
The relative density of the test substance was determined according to EC method A.3 and OECD 109. The relative density ("D" _"4" ^"20" ) of the test substance was determined to be 1.4408 relating to the density of water at 4 °C (0.999972 g/cm3).

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