Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6.alpha.,11.beta.,16.alpha.,17.alpha.)-

Flammability

Link to relevant study record(s)

Reference

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

29 April 2003 - 9 May 2003

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.10 (Flammability (Solids))

Version / remarks:

The fire train test was performed in accordance with SOP, LP-06. Method used is based on EU method A.10

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Specific details on test material used for the study:

Moisture content: 0.5% w/w
Batch Number: H03421

Test procedure:

burning rate test over 100 mm length

Burning time:

0 s

Moisture (wt %):

0.5

Remarks on result:

other: combustion localised to ignition source

Six fire train tests were performed on the test substance at room temperature (21°C). The fire did not propagate along the train during this test. The substance was observed to support localised combustion.

Test 1: No burning observed

Test 2: No burning observed

Test 3: No burning observed

Test 4: No burning observed

Test 5: No burning observed

Test 6: No burning observed

Interpretation of results:

GHS criteria not met

Conclusions:

Substance is non-combustible

Executive summary:

Flammability of thioacid was evaluated through a train fire test, based on EU method A.10 (Official Journal of the European Communities L383). A sample of the material was supplied by GlaxoSmithKline for the purposes of this test. The test concluded that the material is classified as a non-combustible solid and will not support propagating combustion. It can support combustion in the vicinity of a very hot ignition source.

Description of key information

Flammability of thioacid was evaluated through a train fire test, based on EU method A.10 (Official Journal of the European Communities L383). The test concluded that the material is classified as a non-combustible solid and will not support propagating combustion.

Key value for chemical safety assessment

Flammability:

not classified

Justification for classification or non-classification

A train fire (10 cm) test, based on EU method A.10 under GLP conditions, concluded that it is non-combustible and will not propagate ignition. The test substance supported localised combustion but flame propagation was not observed during the tests, so the criteria for classification as a flammable solid (section 2.7.2 of Annex I of CLP) are not fulfilled.