Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 617-081-9
CAS number: 80473-92-3
From the results of the study, the toxicity rating for GR46580X
(Thio-acid) was harmful.
The acute oral toxicity of GR46580X was evaluated in CR/H mice. The test
material was administered by gavage as suspensions in 0.5% aqueous
Methocel K15M Premium (hydroxypropyl methyl cellulose, viscosity type
15000). Groups of 10 mice (5 male, 5 female) were used. The animals were
observed for up to 14 days after dosing. The acute oral toxicity of the
test material was assessed on the basis of clinical signs.
Clinical signs of toxicity were noted in both sexes on the day of dosing
with 2000 mg/kg GR46580X and one female was killed in extremis
one day after dosing. There were no clinical signs of toxicity at a dose
level of 200 mg/kg GR46580X and the material was classified as harmful.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again