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Administrative data

Description of key information

The acute oral LD50of 2-(N-ethylanilino) ethanol in Wistar rats is > 2000 mg/kg body weight.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Since no mortality or any visible sub-lethal effects occurred in six animals tested, there is no reason to expect significant mortality between 2000 and 5000 mg/kg body weight.

Justification for classification or non-classification

According to CLP, the substance is not classified since the LD50 is > 2000 mg/kg bw.

According to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS 2017):  Category 5 or Unclassified.

For reasons of animal welfare concern, testing of animals in GHS Category 5 ranges (2000-5000 mg/kg) is discouraged and should only be considered when there is a strong likelihood that results of such a test have a direct relevance for protecting human or animal health or the environment.