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Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Reference
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
April 2004
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method C.2 (Acute Toxicity for Daphnia)
Version / remarks:
EC No. 440/2008
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Specific details on test material used for the study:
Physical state/Appearance: Brown Liquid
Batch: 15B26
Purity: 81.7%
Expiry Date: 01 August 2016
Storage Conditions: Room temperature, in the dark, under nitrogen
Analytical monitoring:
yes
Vehicle:
yes
Test organisms (species):
Daphnia magna
Test type:
static
Water media type:
other: reconstituted water
Remarks:
ISO medium
Limit test:
no
Total exposure duration:
48 h
Hardness:
250 mg/L as CaCo3
Test temperature:
18 - 22 deg C
pH:
7.8
Dissolved oxygen:
approximately air-saturation value
Reference substance (positive control):
yes
Remarks:
Potassium dichromate 0.32 - 3.2 mg/L. NOEC 24/48h = 0.56/0.32 mg/L LOEC 24/48h = 1.0/0.56
Key result
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
240 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Key result
Duration:
48 h
Dose descriptor:
LOEC
Effect conc.:
200 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
yes
Conclusions:
Time Point (Hours): 48
EC50(mg/L): 240
95% confidence limits (mg/L): 190-310
NOEC (mg/L): 100
LOEC (mg/L): 200

Description of key information

Time Point (Hours)              EC50(mg/L)              95% confidence limits (mg/L)              NOEC (mg/L)              LOEC (mg/L)

48                                          240                            190-310                                                  100                            200

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
240 mg/L

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