Registration Dossier
Registration Dossier
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EC number: 202-716-0 | CAS number: 98-95-3
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Allergien gegenüber aromatischen Amino- und Nitroverbindungen.
- Author:
- Schulz, K.H.
- Year:
- 1 962
- Bibliographic source:
- Berufsdermatosen 10, 69-91
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- Epicutaneous test with patients suffering from dermatitis.
- GLP compliance:
- no
Test material
- Reference substance name:
- Nitrobenzene
- EC Number:
- 202-716-0
- EC Name:
- Nitrobenzene
- Cas Number:
- 98-95-3
- Molecular formula:
- C6H5NO2
- IUPAC Name:
- nitrobenzene
- Details on test material:
- - Name of test material (as cited in study report): nitrobenzene
- Analytical purity: no data
Constituent 1
Method
- Type of population:
- general
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Epicutaneous tests for the evaluation of nitrobenzene (applied concentration 1%) as a potential sensitizer in 3
persons were negative (no details specified).
3/15 persons, sensitized by p-phenyldiamine or azo-dyes showed a weak reaction to nitrobenzene.
Applicant's summary and conclusion
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