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EC number: 232-565-6
CAS number: 9000-90-2
Effects: May cause allergic respiratory reaction.
Symptoms: Shortness of breath, wheezing and coughing. The effect of inhalation may be delayed.
First Aid: Remove person to fresh air. If signs/symptoms continue, get medical attention. Show the safety data sheet to the doctor in attendance.
Effects: May cause slight irritation.
Symptoms: Slight irritation.
First Aid: Remove and wash contaminated clothing before re-use. Wash off immediately with plenty of water. If symptoms persist, call a doctor. Show the safety data to the doctor in attendance.
First Aid: Hold eye open and rinse slowly and gently with water for 15-20 min. Remove contact lenses, if present, after the first five minutes, then continue rinsing the eye. If symptoms persist, call a doctor. Show the safety data sheet to the doctor in attendance.
Effects: Ingestion may cause gastrointestinal irritation.
First Aid: Rinse mouth with water and drink plenty of water. If symptoms persist, call a doctor. Show the safety data sheet to the doctor in attendance.
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable Extinguishing Media: none.
Hazardous combustion products: On burning, this material may generate toxic gases such as oxides of carbon, nitrogen and sulphur.
Specific hazards arising from the chemical: May cause an allergic respiratory reaction.
Protective equipment and precautions for firefighters: Self-contained breathing apparatus.
Wear suitable personal protection:
Respiratory Protection: In case of insufficient ventilation wear suitable respiratory equipment with P3 filter.
Eye protection: Safety glasses with side-shields.
Skin Protection: Long sleeved clothing.
Hand Protection: Protective gloves.
Environmental precautions: Prevent the material from entering surface water or sanitary sewer system. Do not discharge directly to a water source. If accidental spillage or washings enter drains or watercourses contact the local Environmental Authorities.
Methods for cleaning up: Avoid formation of dust and aerosols. Spilled preparation should be removed immediately to avoid formation of dust. Take up by mechanical means preferably by a vacuum cleaner equipped with a high efficiency filter. Flush remainder carefully with plenty of water. Avoid splashing and high pressure washing (avoid formation of aerosols). Ensure sufficient ventilation. Wash contaminated clothing.
Avoid formation of dust and aerosols. Ensure adequate ventilation
Keep tightly closed in a dry and cool place.Temperature 0-25°C (32°F-77°F)
Storage conditions: In unbroken packaging - dry and protected from the sun.
Due to the intrinsic hazard for respiratory sensitization which is associated to enzymes, the industry and its trade associations have over the years developed and updated several guidelines on the safe industrial handling of enzyme products, and guidelines on the development of safe enzyme containing consumer products. Workshops on these issues have also been arranged by the trade associations in order to convey product stewardship and to ensure correct risk management. Examples of such guidelines are shown below:
• Amfep, 2013. Association of Manufacturers of Fermentation Enzyme Products. October 2013; “Guide to the safe handling of industrial enzyme preparations”. 12 pages. Brussels http://www.amfep.org/content/safe-handling-guide-2013
First edition published in 2001
• AISE, 2013. The international Association for Soaps, Detergents and Maintenance Products. September 2013; “Guiding principles for the safe handling of enzymes in detergent manufacture”. 122 pages . Brussels www.aise-net.org
First edition published in 2002
• AISE, 2013. The international Association for Soaps, Detergents and Maintenance Products. September 2013; “Exposure measurements of enzymes for risk assessment of household cleaning spray products”. Brussels http://www.aise.eu/publications.php?cat=A.I.S.E.
First edition published in 2010
• Novozymes A/S, 2012. Poster illustrating safe handling of granulated enzyme products, and poster illustrating safe handling of liquid enzyme products. Available from Novozymes customer site.
• Novozymes A/S, 2011. “Enzymes and You”. Bagsvaerd DK. 51 pages. Available from Novozymes customer site.
First edition published in 1992
• Novozymes A/S, 2007. “Safe handling of enzymes”. Bagsvaerd DK. 38 pages. Available from Novozymes customer site.
• AISE, 2006. The international Association for Soaps, Detergents and Maintenance Products. 2006; “Developing consumer products containing enzymes: Ensuring consumer safety”. Brussels www.aise-net.org
• Amfep, 2006. Association of Manufacturers of Fermentation Enzyme Products. February 2006; “Amfep and ETA position on consumer risk assessments for enzyme-containing personal care products and cosmetics”. Brussels http://amfep.drupalgardens.com/sites/amfep.drupalgardens.com/files/Amfep-ETA-position-Cosmetics.pdf#overlay-context=content/documents
First edition published in 1999
• US SDA, 2005. The Soap and Detergent Association (SDA). Risk Assessment Guidance for Enzyme-containing Products. US Soap and Detergent Association, Washington, DC. 58 pages. http://www.cleaninginstitute.org/science/enzyme_safety.aspx
• US SDA, 1995. The Soap and Detergent Association (SDA). “Work practices for handling enzymes in the detergent industry”. New York: The Soap and Detergent Association. 55 pages. http://www.cleaninginstitute.org/science/enzyme_safety.aspx
• SDIA 1991. The Soap and Detergent Industry Association (merged into AISE in 1999 ?) “The Standing Committee on Enzymatic Washing Products, Revised Operating Guidelines, Fifth Report”. London.
First edition published in 1969
• SDIA 1971. The Soap and Detergent Industry Association (merged into AISE in 1999 ?) “Recommended Operating Procedures for UK Factories Handling Enzyme Materials”. London. The Annals of Occupational Hygiene, June 1971, Vol 14 Issue: 2 p71-83.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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